Until now, many forms of severe inherited hearing loss have been managed with assistive devices such as hearing aids and cochlear implants. Today, a first-of-its-kind gene therapy may offer new hope for patients with a rare mutation in the OTOF gene, which plays an essential role in transmitting sound signals from the inner ear to the brain. Dr. Ksenia Aaron, a leading otolaryngologist at Rambam Health Care Campus (Rambam), offers her perspective on this breakthrough in auditory medicine.