The Center for Kidney Disease Research is an interdisciplinary research hub dedicated to elucidating the molecular, cellular, genetic, and translational mechanisms that underlie kidney disease across the human lifespan. The center integrates complementary areas of expertise spanning pediatric rare nephropathies, APOL1-associated kidney disease, podocyte biology, diabetic kidney disease, and chronic kidney disease (CKD) progression, with the overarching objective of advancing mechanistic understanding and improving translational relevance in nephrology research. Kidney disease represents a major and growing global health burden, yet the biological processes governing disease susceptibility, phenotypic variability, and progression remain incompletely understood. The Center addresses this challenge through a research framework that combines mechanistic biology with human disease investigation, integrating experimental systems, patient-derived data, genomics, and population-level analyses.
The Center for Kidney Disease Research is an interdisciplinary research hub dedicated to elucidating the molecular, cellular, genetic, and translational mechanisms that underlie kidney disease across the human lifespan. The center integrates complementary areas of expertise spanning pediatric rare nephropathies, APOL1-associated kidney disease, podocyte biology, diabetic kidney disease, and chronic kidney disease (CKD) progression, with the overarching objective of advancing mechanistic understanding and improving translational relevance in nephrology research. Kidney disease represents a major and growing global health burden, yet the biological processes governing disease susceptibility, phenotypic variability, and progression remain incompletely understood. The Center addresses this challenge through a research framework that combines mechanistic biology with human disease investigation, integrating experimental systems, patient-derived data, genomics, and population-level analyses. The Center maintains a strongly translational orientation through close integration with clinical nephrology programs and international collaborative networks, we leverage diverse patient cohorts, advanced genomic approaches, and mechanistic experimental models to establish biologically meaningful connections between molecular discovery and human disease. The Center encompasses three different, yet complementary, research labs and so provides a unique platform for studying renal disease across developmental and pathological contexts.