Laboratory for Bone Repair

The Laboratory for Bone Repair is located at the Clinical Research Institute at Rambam (CRIR).  Our research is focused on bone regeneration via scaffolds, cells and growth factors. 

Our primary research involves endothelial progenitor cells (EPC): isolation, cell culture, characterization, and local transplantation of EPCs to enhance bone healing in several bone pathologies (e.g: extra-cortical bone formation, bisphosphanate osteonecrosis of the jaw, peri-implantitis and healing of large jaw bone defects). Currently our research expanded to investigate the mechanism of EPC in bone and blood vessel formation.    Our team is made of clinicians (Medical and Dental surgeons) and other investigators with various expertise. We also collaborate with many other leading laboratories, researchers and industries worldwide. Our vision is to improve treatments that involve bone regeneration in orthopedic, maxillofacial and neurosurgery. We envision to take cell therapy to the next level from the bench to the bed.