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Stem Cells and Regenerative Medicine

The breakthrough discovery by Professor Joseph Itskovitz–Eldor and colleagues in human embryonic stem cells emanates from Rambam’s long standing leadership in woman’s health and advanced reproductive technologies. Human embryonic stem cells are being used by Rambam research scientists in a broad range of research projects, whose common aim is to derive specialized cell types for the treatment of patients who have developed common forms of organ system failure, such as heart failure, neurodegenerative disease and diabetes.

The experimental development of a biological pacemaker and the demonstration of insulin production by derivatives of human embryonic stem cells are but two examples of the remarkable progress in this area.
In addition, human embryonic stem cells are being used by Rambam scientists as a biotechnological platform for drug discovery and testing, gene discovery, as well as aging and cancer research. In the latter regard, it is increasingly appreciated that normal non-tumor cells surrounding a cancer growth represent an important target in anti-cancer therapy. Human embryonic stem cells provide a unique platform for developing such therapeutic strategies. Rambam Faculty have also been at the forefront of public discourse regarding the societal and ethical repercussions of human embryonic stem cell technology.